It's best to download the file as a PDF and upload it directly in the room as a file. Keep in mind, animations and embedded videos will not play. It is suggested to download them from your file and upload and play them as MP4s in the Virtual Studio.
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But, you can also choose to share directly from the Keynote application via Screen Share. You will need to use the screen share feature within the Virtual Studio. This feature is only accessible to moderators and speakers. Keep in mind animations and embedded videos will most likely not play successfully as the frame rate when screen sharing is slower than normal video playback.
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Make sure to open the Keynote presentation on your desktop prior to sharing your screen.
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Once you have your opened your Keynote Presentation, you will need to edit the layout to prevent attendees from seeing your notes and and other layout settings.
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From the Keynote navigation up top, select View.

Then check Slide Only.

Then choose Inspector and Hide Inspector.

Lastly, click Enter Full Screen.

Once you've edited the layout of the presentation, just share the presentation via screen share.
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Click the Screen Button from the Sharing Toolbar in the bottom center of your screen.

Then Choose Application Window.

Then select your Keynote File from your desktop and begin sharing it.